From molecule design to monitoring:
The science behind extended half-life rFVIII products

Bayer Satellite Symposium

 

At the 64th Annual ISTH SSC Meeting | Dublin, Ireland

Friday, July 20, 2018 | 13:15–14:30 | Wicklow Hall 2, Level 2, The Convention Centre Dublin

Join our expert faculty as they first explore the science behind common extended half-life (EHL) strategies, the impact these may have on a product’s pharmacokinetic (PK) profile, and what this means for clinical practice. The panel will then review the practical aspects of monitoring patient response to EHL products in the clinical setting and finally consider the changing clinical landscape and the challenges this may present in terms of patient monitoring in the future.

Chair: Professor Johannes Oldenburg

(Institute of Experimental Hematology and Transfusion Medicine, University Clinic Bonn, Germany)

TOPIC

SPEAKER

Welcome and introduction

Johannes Oldenburg

(Institute of Experimental Hematology and

Transfusion Medicine, University Clinic Bonn, Germany)

Examining EHL molecules:

Common strategies for prolonging protection

Elena Santagostino

(Angelo Bianchi Bonomi Hemophilia and Thrombosis Center

of the IRCCS Ca’ Granda Foundation, Maggiore Hospital,

Milan, Italy)

Investigating the impact of EHL technologies: The PK perspective

Alfonso Iorio

(McMaster University, Hamilton, Canada)

Considering current and future challenges

of monitoring treatment in the changing

clinical landscape

Steven Kitchen

(Sheffield Haemophilia and Thrombosis Centre,

Royal Hallamshire Hospital, UK)

Panel discussion and Q&A

Johannes Oldenburg

(Institute of Experimental Hematology and

Transfusion Medicine, University Clinic Bonn, Germany)

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